What is THCA? THCA is actually a non-intoxicating compound that doesn't produce the psychoactive effects associated with THC, the compound THCA is converted into when heated. THC vs. THCA: THCA is NON-psychoactive in it's raw, natural plant form. THCA must be heated to create THC, through smoking, vaping, dabbing, or cooking for edibles. This conversion alters the molecular structure of THCA by removing a carboxyl ring. This also helps THC bind to CB1 receptors in our bodies. Effects-wise, THCA and THC overlap in some areas. Both have potential to treat nausea, but THCA shows far more promise for addressing inflammation. On the flip side, because THCA isn’t intoxicating, some may find it less effective for sleep than activated THC. And while THC isn’t recommended for seizure disorders, THCA may show some promise in addressing those conditions.